MyBioSource.com's CD3 Antibody is a Mouse monoclonal antibody. The CD3 Antibody was generated using CD247, CD3 zeta, CD3-eta, CD3Q, and TCR zeta chain as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, and Immunohistochemistry.
Description
Background: CD3 is a component of T cell surface receptor (TCR), it cantains 5 invariable chains. gamma-, delta-, epsilon-, and zeta/eta‚Clevers et al. (1988) showed the TCR/CD3 complex consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits, CD3 is responsible for the signal transduction of the TCR